[HTML][HTML] Desogestrel plus testosterone effectively suppresses spermatogenesis but also causes modest weight gain and high-density lipoprotein suppression
BD Anawalt, KL Herbst, AM Matsumoto, TMT Mulders… - Fertility and sterility, 2000 - Elsevier
Objective: To test the hypothesis that oral desogestrel (DSG) plus testosterone would
uniformly and rapidly suppress sperm concentrations in young men as effectively as
levonorgestrel (LNG) plus testosterone and cause less high-density lipoprotein (HDL)
suppression and weight gain. Design: Single-blind, randomized trial. Setting: VA Puget
Sound and University of Washington, Seattle, Washington. Patient (s): Twenty-four healthy
young men, aged 20–49. Intervention (s): Subjects were randomized to three groups of men …
uniformly and rapidly suppress sperm concentrations in young men as effectively as
levonorgestrel (LNG) plus testosterone and cause less high-density lipoprotein (HDL)
suppression and weight gain. Design: Single-blind, randomized trial. Setting: VA Puget
Sound and University of Washington, Seattle, Washington. Patient (s): Twenty-four healthy
young men, aged 20–49. Intervention (s): Subjects were randomized to three groups of men …
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